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A comparative study of Garlic extract activity versus antibacterial agents against bacterial pathogens isolated from females with acne in Shendi city

Eman Amer Mohammed Nor , Waseem Sameer Kwami

Eman Amer Mohammed Nor 1 , Waseem Sameer Kwami 1

1Department of Microbiology, Faculty of Medical Laboratory Sciences, University of Shendi, Sudan. sameerw77@yahoo.com

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Abstract

Introduction: Traditional herbal medicines provide an interesting and unexplored source for the anti-acne development, such as garlic (Allium sativum), This was descriptive cross-sectional community based study, conducted in Shendi city, to compare the activity of Garlic extract versus antimicrobial therapy against bacterial pathogens isolated from females with acne. Method: A total of 75 skin swabs from acne lesions, were collected from female patients, and then inoculated on blood agar, incubated at 37c for 3 days anaerobically. The growing isolates were identified according to their colonial morphology, indirect gram staining reaction, and biochemical tests. Results: The study denoted that the age group (20-30 year) was the most age affected by acne 60 (80%) and S. aureus was responsible from most of acne cases 48 (64%), while S. epidermidis was responsible only from 15 (20%) of acne cases.In this study the garlic extract showed prominent activity (100%) against all isolated species of Staphylococcus aureus and Staphylococcus epidermidis in contrast to activity of selected antimicrobial agents in which Staphylococcus aureus strains showed (97.9% to doxycycline, 93.8% to Co-trimoxazole, 91.7% to Clindamycin, 91.7% to Vancomycin, and 97.9% to Levofloxacin), and Staphylococcus epidermidis strains showed (100% to doxycycline, 100% to Co-trimoxazole, 100% to Clindamycin, 100% to Levofloxacin, and 86.7% to Vancomycin). Conclusion: The study concluded that the most two common bacterial species isolated from acne lesions were S.aureus and S.epidermidis and the garlic extract showed 100% activity against both S.aureus and S.epidermidis strains.
Keywords: Acne, Bacterial pathogens, Females, Garlic, Shendi.

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